| 1. | Detroit Lions: Matt Stafford, QB, Georgia |
| 2. | St. Louis Rams: Jason Smith, OT, Baylor |
| 3. | KC Chiefs: Aaron Curry, OLB, WF |
| 4. | Seattle Seahawks: Michael Crabtree, WR, TTU |
| 5. | Cleveland Browns: Brian Orakpo, DE/OLB, UT |
| 6. | Cincinnati Bengals: B.J. Raji, DE, BC |
| 7. | Oakland Raiders: Jeremy Maclin, WR, Mizzou |
| 8. | Jacksonville Jaguars: Eugene Monroe, OT, UVA |
| 9. | Green Bay Packers: Everette Brown, DE, FSU |
| 10. | San Francisco 49ers: Mark Sanchez, QB, USC |
| 11. | Buffalo Bills: Aaron Maybin, DE/OLB, PSU |
| 12. | Denver Broncos: Rey Maualuga, ILB, USC |
| 13. | Washington Redskins: Michael Oher, OT, Ole Miss |
| 14. | New Orleans Saints: Chris “Beanie” Wells, RB, Ohio St. |
| 15. | Houston Texans: Malcom Jenkins, CB/S, Ohio St. |
| 16. | San Diego Chargers: Andre Smith, OT, Bama |
| 17. | NY Jets: James Laurinaitis, ILB, Ohio St. |
| 18. | Denver Broncos: Josh Freeman, QB, KSU |
| 19. | TB Buccaneers: Darius Heyward-Bey, WR, MD |
| 20. | Detroit Lions (Dallas): Brian Cushing, OLB, USC |
| 21. | Philadelphia Eagles: Knowshon Moreno, RB, Georgia |
| 22. | Minnesota Vikings: Eben Britton, OT, AZ |
| 23. | NE Patriots: Vontae Davis, CB, ILL |
| 24. | Atlanta Falcons: Louis Delmas, FS, W. Mich |
| 25. | Miami Dolphins: Clay Mathews, OLB, USC |
| 26. | Baltimore Ravens: Alphonso Smith, CB, WF |
| 27. | Indianapolis Colts: Perria Jerry, DT, Ole Miss |
| 28. | Eagles (Carolina): Brandon Pettigrew, TE, Ok. St. |
| 29. | NY Giants: Percy Harvin, WR, Florida |
| 30. | Tennessee Titans: Robert Ayers, DE, Tennesee |
| 31. | Arizona Cardinals: Larry English, DE, No. ILL |
| 32. | Pittsburgh Steelers: William Beatty, OT, UConn |
| 33. | Detroit Lions: Tyson Jackson, DE, LSU |
| 34. | NE Patriots (KC): Duke Robinson, OT/G, OU |
| 35. | St. Louis Rams: Lesean McCoy, RB, Pitt |
| 36. | Cleveland Browns: Sen’Derrick Marks, DT, Auburn |
| 37. | Seattle Seahawks: Alex Mack, C, Cal |
| 38. | Cincinnati Bengals: Hakeem Nicks, WR, UNC |
| 39. | Jacksonville Jaguars: William Moore, S, Mizzou |
| 40. | GB Packers: Evander Hood, DT, Mizzou |
| 41. | Oakland Raiders: Troy Kopog, OT, Tulane |
| 42. | Buffalo Bills: Max Unger, C, Oregon |
| 43. | San Francisco 49ers: Fenuki Tupou, OT, OR |
| 44. | Miami (Redskins): D.J. Moore, CB, Vandy |
| 45. | NY Giants (Saints): Kenny Brit, WR, Rutgers |
| 46. | Houston Texans: Ron Brace, NT, BC |
| 47. | Patriots (Chargers): Tyrone McKenzie, OLB, SF |
| 48. | Denver Broncos: Michael Johnson, DE, GT |
| 49. | Chicago Bears: Louis Murphy, WR, UF |
| 50. | Cleveland Browns (Bucs): Alphonso Smith, CB, WF |