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Treatments for Wilsons disease (hepatolenticular degeneration)  
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Tags: Wilsons disease, autosomal recessive, hereditary disease, heterozygous, neurological, treatments

This disease is treated with lifelong use of chelating agents known as D-penicillamine or trientine hydrochloride, drugs that help remove copper from tissue.

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  • This disease is treated with lifelong use of chelating agents known as D-penicillamine or trientine hydrochloride, drugs that help remove copper from tissue.
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  • Patients will also need to take vitamin B6 and follow a low-copper diet, which means avoiding mushrooms, nuts, chocolate, dried fruit, liver, and shellfish.
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  • Consuming extra zinc may be helpful in blocking the intestines' absorption of copper.
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  • Liver transplantation is effective in patients with fulminant Wilson's disease that does not respond to the usual treatment.
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  • Because the primary defect resides within the liver, the transplantation is curative, but as it is only undertaken in severely ill patients the prognosis is still mediocre.

    Lister: BobbysWorld
    Source: Compiled by LAL Editor

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