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Treatments for Renal transplant failure
INFORMATIVE
Tags: Renal transplant failure, Kidney transplantation, organ transplant, acute renal failure, chronic renal failure, treatments
The most critical part of kidney transplantation is preventing rejection of the graft kidney.
| | Different transplant centers use different drug combinations to fight rejection of a transplanted kidney. |
| | The drugs work by suppressing your immune system, which is programmed to reject anything "foreign," such as a new organ. |
| | Some of the most common immune-suppressing drugs used is, |
| | Cyclosporine: This drug interferes with communication between the T cells of the immune system. It is started immediately after the transplant to suppress the immune system and continued indefinitely. |
| | Corticosteroids: These drugs block T-cell communication as well. They are usually given at high doses for a short period immediately after the transplant and again if rejection is suspected. |
| | Azathioprine: This drug slows the production of T cells in the immune system. Azathioprine is usually used for long-term maintenance of immunosuppression. |
| | Newer antirejection drugs include tacrolimus, sirolimus, and mizoribin, among others. |
| | Other costly and experimental treatments include using antibodies to attack specific parts of the immune system to decrease its response. |
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Compiled by LAL Editor
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