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Treatments for Renal transplant failure  
INFORMATIVE User Created List

Tags: Renal transplant failure, Kidney transplantation, organ transplant, acute renal failure, chronic renal failure, treatments

The most critical part of kidney transplantation is preventing rejection of the graft kidney.

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  • Different transplant centers use different drug combinations to fight rejection of a transplanted kidney.
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  • The drugs work by suppressing your immune system, which is programmed to reject anything "foreign," such as a new organ.
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  • Some of the most common immune-suppressing drugs used is,
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  • Cyclosporine: This drug interferes with communication between the T cells of the immune system. It is started immediately after the transplant to suppress the immune system and continued indefinitely.
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  • Corticosteroids: These drugs block T-cell communication as well. They are usually given at high doses for a short period immediately after the transplant and again if rejection is suspected.
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  • Azathioprine: This drug slows the production of T cells in the immune system. Azathioprine is usually used for long-term maintenance of immunosuppression.
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  • Newer antirejection drugs include tacrolimus, sirolimus, and mizoribin, among others.
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  • Other costly and experimental treatments include using antibodies to attack specific parts of the immune system to decrease its response.

    Lister: LisaLisa
    Source: Compiled by LAL Editor

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